Major Depressive Disorder

Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)

Also Known As:

Major Depressive Disorders; Depressive Disorder, Major; Depressive Disorders, Major; Involutional Depression; Involutional Melancholia; Involutional Paraphrenia; Involutional Paraphrenias; Involutional Psychoses; Involutional Psychosis; Paraphrenias, Involutional; Psychoses, Involutional; Depression, Involutional; Melancholia, Involutional; Paraphrenia, Involutional; Psychosis, Involutional

Mental Disorders: 25040
- Mood Disorders: 10172
  - Depressive Disorder: 6686
    - Major Depressive Disorder: 11770

GSRD Consortium Selected Research

GSRD Consortium Research Topics

Disease

Drug/Important Bio-Agent (IBA)